anadrol 50 for sale

Indole derivative having a structural similarity with members of serotonin, as well as with reserpine. Pirlindol has expressed antidepressant activity, a feature of its action is the fact that it timolepticheskogo effect with a balanced action (activating effect in patients with apathetic, anadrol 50 for sale anergic depression, combined with a sedative and anxiolytic effects in patients with agitated states). Selectively inhibits monoamine oxidase blocks the deamination of serotonin and noradrenaline, to a lesser extent – tyramine partially inhibits the reuptake of monoamines. It activates the processes of synaptic transmission of nerve excitation in the central nervous system.Weakens the depressive effects of reserpine, enhances the action of norepinephrine precursor – dihydroxyphenylalanine (L-dopa), stimulates the adrenergic structures; potentiates the effects of serotonin precursor – 5 oksitriptofana (stimulates serotonergic structures). Unlike tricyclic antidepressants, has no anticholinergic effect. Has also nootropic effect, improves cognitive (cognitive) function. Pirlindol not cumulated in the body, has no tolerance does not cause dependence or withdrawal. Pirlindol almost completely absorbed from the gastrointestinal tract. After receiving anadrol for sale a single dose maximum concentration of active compound in plasma is achieved in 2-8 hours. Pirlindol subject to enterohepatic circulation. Elimination from the plasma is carried out three phase. The absolute bioavailability of 20-30%, since there is a pronounced first-pass metabolism in the liver. Pirlindol binds strongly to plasma proteins (95%), so the anadrol 50 for sale terminal during its half-life is long – 185 hours. Pirlindol almost completely metabolized and only a very small amount of it is excreted in the urine in unchanged form. From the body about 50-70% of the metabolites excreted in the urine, 25-45% – in the bile through the intestines.

Indications Depression different genesis, mostly with psychomotor retardation and asthenic disorders with anxiety, depression or anxiety and delusional component. Involutionary depression. Alcohol withdrawal syndrome, Alzheimer’s disease (in the complex therapy).

Contraindications Individual hypersensitivity to the drug, acute hepatitis, blood system diseases, concomitant use with MAO inhibitors (see. “Special Instructions”).

Use of the drug during pregnancy and lactation is not recommended. There are no adequate and well-controlled clinical trials of the drug during pregnancy and lactation. It is known that the use of tricyclic antidepressants and similar drugs in the third trimester of pregnancy may cause the newborn tachycardia, irritability, muscle cramps. Use of the drug is allowed only if the benefit to the mother outweighs the potential risk to the fetus.

Dosing and dose Inside of 50-75 mg (0.05 – 0.075 g) in two hours and gradually increasing the dose of 25 -50 mg to 150 – 300 mg (0.15 – 0.30 grams) per day. The maximum daily dose – 400 mg divided into 2-3 doses. After reaching the therapeutic effect of the treatment is sustained individually selected dose for 2-4 weeks, after which the dose gradually.

Side effects: dry mouth, sweating, tremor, tachycardia, nausea, dizziness, allergic reactions.

Overdose Pirlindol low toxicity. Cases of overdose have not been described in humans. With long-term repeated administration anadrol 50 pirlindola experimental animals at doses much higher than therapeutic, not mentioned the most important pathological disorders of organs and their systems. Very high doses cause convulsions in animals, which can be cut short diazepam.

Interaction with other drugs Normazidol not prescribed in conjunction with other MAO inhibitors, furazolidone, procarbazine, selegiline. It improves the effectiveness of epinephrine (due to antimonoaminoksidaznoy activity). Compatible with antipsychotics, anxiolytics. During therapy, you can not drink alcohol.

Cautions after use of anadrol 50 for saleinhibitors treatment begin no earlier than 14 days. The absence of anticholinergic action allows the use in patients with glaucoma and prostate adenoma

Effects on ability to drive vehicles: Caution should be exercised, as the speed of the reaction can be reduced. kob steroider female bodybuilding workout liquid steel reviews bodybuilding shirt